full transcript
From the Ted Talk by Kaitlyn Sadtler and Heather J. Faust: Why haven't we cured arthritis?
Unscramble the Blue Letters
Even the most cmoomn type, osteoarthritis, is trickier to prevent than one might think. It’s a general misconception that arthritis is confined to old age. The origins of osteoarthritis can often be traced to a patient’s early life, from any seemingly ordinary joint iurnjy. Following impact, immune clles rush in to help clean and rpaier the damaged site and begin pumping out enzymes, including matrix metalloproteinases and aggrecanases. These enzymes clear out the damaged tissue and contribute to inflammation. But while this rapid sellniwg helps protect the jonit during recovery, inadequately healed tissue can cause these immune cells to overstay their welcome. The continuing flood of enzymes starts to degrade the calitagre, wenieankg the joint and leading to aiirtrhts later on.
Open Cloze
Even the most ______ type, osteoarthritis, is trickier to prevent than one might think. It’s a general misconception that arthritis is confined to old age. The origins of osteoarthritis can often be traced to a patient’s early life, from any seemingly ordinary joint ______. Following impact, immune _____ rush in to help clean and ______ the damaged site and begin pumping out enzymes, including matrix metalloproteinases and aggrecanases. These enzymes clear out the damaged tissue and contribute to inflammation. But while this rapid ________ helps protect the _____ during recovery, inadequately healed tissue can cause these immune cells to overstay their welcome. The continuing flood of enzymes starts to degrade the _________, _________ the joint and leading to _________ later on.
Solution
- arthritis
- swelling
- common
- joint
- cartilage
- cells
- repair
- injury
- weakening
Original Text
Even the most common type, osteoarthritis, is trickier to prevent than one might think. It’s a general misconception that arthritis is confined to old age. The origins of osteoarthritis can often be traced to a patient’s early life, from any seemingly ordinary joint injury. Following impact, immune cells rush in to help clean and repair the damaged site and begin pumping out enzymes, including matrix metalloproteinases and aggrecanases. These enzymes clear out the damaged tissue and contribute to inflammation. But while this rapid swelling helps protect the joint during recovery, inadequately healed tissue can cause these immune cells to overstay their welcome. The continuing flood of enzymes starts to degrade the cartilage, weakening the joint and leading to arthritis later on.
Frequently Occurring Word Combinations
ngrams of length 2
collocation |
frequency |
immune cells |
3 |
arthritic conditions |
2 |
joint pain |
2 |
Important Words
- age
- aggrecanases
- arthritis
- cartilage
- cells
- clean
- clear
- common
- confined
- continuing
- contribute
- damaged
- degrade
- early
- enzymes
- flood
- general
- healed
- helps
- immune
- impact
- inadequately
- including
- inflammation
- injury
- joint
- leading
- life
- matrix
- metalloproteinases
- misconception
- ordinary
- origins
- osteoarthritis
- overstay
- prevent
- protect
- pumping
- rapid
- recovery
- repair
- rush
- seemingly
- site
- starts
- swelling
- tissue
- traced
- trickier
- type
- weakening